Parthenolide enhances the metronomic chemotherapy effect of cyclophosphamide in lung cancer by inhibiting the NF-kB signaling pathway

Figure 1 P450 expression detection in different cell lines and the effect of its overexpression on Lewis lung cancer cells cell activity. A: Q-PCR detection of P450 mRNA expression in Lewis lung cancer cells (LLC) cells transfected with P450 overexpression plasmid (P450-OE); B: Western blot detection of P450 protein in different cell lines. Full undamaged Gels and Blots images are shown in Supplementary Figure 1; C: CCK8 assay of LLC cells transfected with P450-OE plasmid or the vector plasmid. n = 3, ^dP < 0.0001; NS: Not significant; LCC: Lewis lung cancer cells.