Bibliometric analysis of phosphoglycerate kinase 1 expression in breast cancer and its distinct upregulation in triple-negative breast cancer

Figure 6 Thematic plot of research on breast cancer and phosphoglycerate kinase 1 and trends in topics related to breast cancer and phosphoglycerate kinase 1 research. A: Using Web of Science key words, various research themes were detected via co-occurrence analysis and walktrap clustering analysis. Different colors represent different themes. Density represents the connection strength of basic knowledge units within a single topic. A larger topic density value indicates greater topic maturity. Centrality represents the strength of the connection between a topic and other topics. A higher centrality value of a topic suggests a strong interconnection with other topics, placing the topic at the heart of the research landscape. According to the density and centripetal degree values, the rectangular coordinate system was divided into four quadrants. The first quadrant contains core themes of high maturity; the second quadrant has isolated themes of high maturity, and the third quadrant contains new themes or themes that are about to disappear. The fourth quadrant encompasses basic themes of low maturity that may become research hotspots or future research trends; B: Topic trends were detected using co-word analysis. For each topic, the quartiles of publication year were calculated. The horizontal axis represents the first and third quantile years. Each node refers to the median publication year of each term. The larger the node, the more frequent the term.