Low testing rates and high BRCA prevalence: Poly (ADP-ribose) polymerase inhibitor use in Middle East BRCA/homologous recombination deficiency-positive cancer patients

doi:10.5306/wjco.v15.i7.848

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Jul 24, 2024 (publication date) through Jul 16, 2024

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Jul 24, 2024; 15(7): 848-858
Published online Jul 24, 2024. doi: 10.5306/wjco.v15.i7.848

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Figure 3 Response status to chemotherapy of breast and ovarian cancers with and without mutations. Homologous recombination-deficient (HRD) ovarian cancer (n = 6) had a higher percentage of complete remission (3/6) than cancer not HRD (3/19). While germline BRCA gene non-mutated breast cancer (n = 42) patients showed a slightly higher complete response rate (19/42), the overall treatment response remained similar in both mutated and non-mutated groups.

Citation: Syed N, Chintakuntlawar AV, Vilasini D, Al Salami AM, Al Hasan R, Afrooz I, Uttam Chandani K, Chandani AU, Chehal A. Low testing rates and high BRCA prevalence: Poly (ADP-ribose) polymerase inhibitor use in Middle East BRCA/homologous recombination deficiency-positive cancer patients. World J Clin Oncol 2024; 15(7): 848-858
URL: https://www.wjgnet.com/2218-4333/full/v15/i7/848.htm
DOI: https://dx.doi.org/10.5306/wjco.v15.i7.848