Copyright
©The Author(s) 2024.
World J Clin Oncol. Jun 24, 2024; 15(6): 755-764
Published online Jun 24, 2024. doi: 10.5306/wjco.v15.i6.755
Published online Jun 24, 2024. doi: 10.5306/wjco.v15.i6.755
Figure 5 Tankyrase 2 overexpression promotes the malignant behavior of lung cancer cells.
Tankyrase 2 dissociates the destruction complex containing axins, thereby enhancing the stability of β-catenin. Activated β-catenin translocates into the nucleus, where it activates target genes, which contribute to the malignant behavior of lung cancer cells.
- Citation: Wang Y, Zhang YJ. Tankyrase 2 promotes lung cancer cell malignancy. World J Clin Oncol 2024; 15(6): 755-764
- URL: https://www.wjgnet.com/2218-4333/full/v15/i6/755.htm
- DOI: https://dx.doi.org/10.5306/wjco.v15.i6.755