Basic Study
Copyright ©The Author(s) 2024.
World J Clin Oncol. Jun 24, 2024; 15(6): 755-764
Published online Jun 24, 2024. doi: 10.5306/wjco.v15.i6.755
Figure 5
Figure 5 Tankyrase 2 overexpression promotes the malignant behavior of lung cancer cells. Tankyrase 2 dissociates the destruction complex containing axins, thereby enhancing the stability of β-catenin. Activated β-catenin translocates into the nucleus, where it activates target genes, which contribute to the malignant behavior of lung cancer cells.