Tankyrase 2 promotes lung cancer cell malignancy

Figure 2 Effects of tankyrase 2 knockdown or overexpression on proliferation of non-small cell lung cancer cells. A: Proliferative ability of H647 cells transfected with shTNKS2 and A549 cells with tankyrase 2 (TNKS2) overexpression; B: Apoptosis of non-small cell lung cancer cells assessed by flow cytometry. Apoptotic rate of shTNKS2-transfected H647 cells and TNKS2-overexpressing A549 cells was calculated; C and D: Migration ability of H647 cells transfected with shTNKS2 and A549 cells transfected with a TNKS2 overexpression vector at 24 h after transfection (magnification, × 100). ^aP < 0.05; ^bP < 0.01.