Comparative effectiveness of immunotherapy and chemotherapy in patients with metastatic colorectal cancer stratified by microsatellite instability status

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Apr 24, 2024 (publication date) through Jan 25, 2025

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Apr 24, 2024; 15(4): 540-547
Published online Apr 24, 2024. doi: 10.5306/wjco.v15.i4.540

Table 2 Comparative analysis of survival outcomes

Survival analysis	Microsatellite instability-high		Microsatellite stable
Immunotherapy vs chemotherapy	Hazard ratio (95%CI)	Adjusted hazard ratio (95%CI)	Hazard ratio (95%CI)	Adjusted hazard ratio (95%CI)
Overall	0.75 (0.57-0.99)	0.57 (0.43-0.77)	1.05 (0.77-1.43)	0.94 (0.69-1.29)
One year	1.32 (0.92-1.92)	1.23 (0.84-1.81)	1.43 (0.95-2.14)	1.37 (0.91-2.06)
Three year	0.74 (0.56-0.98)	0.62 (0.46-0.82)	0.98 (0.72-1.34)	0.88 (0.65-1.21)

Citation: Niu CG, Zhang J, Rao AV, Joshi U, Okolo P. Comparative effectiveness of immunotherapy and chemotherapy in patients with metastatic colorectal cancer stratified by microsatellite instability status. World J Clin Oncol 2024; 15(4): 540-547
URL: https://www.wjgnet.com/2218-4333/full/v15/i4/540.htm
DOI: https://dx.doi.org/10.5306/wjco.v15.i4.540