Establishment of a prognosis predictive model for liver cancer based on expression of genes involved in the ubiquitin-proteasome pathway

doi:10.5306/wjco.v15.i3.434

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical and Translational Research

World J Clin Oncol. Mar 24, 2024; 15(3): 434-446
Published online Mar 24, 2024. doi: 10.5306/wjco.v15.i3.434

Table 2 The five genes significantly correlate with the prognosis of patients with liver cancer

Gene	Gene set	Coef	Hazard ratio	Z	P value
ATG10	Ubiquitin-conjugating enzyme (E2)	0.48387	1.62234	2.364	0.0181
PSMA8	Proteasome	0.20721	1.23024	1.962	0.0497
PSMB2	Proteasome	0.66763	1.94962	2.483	0.013
USP17L2	Deubiquitinating enzyme (DUB)	-2.8057	0.06046	-3.048	0.0023
USP8	Deubiquitinating enzyme (DUB)	-0.46594	0.62755	-1.701	0.0889

ATG10: Autophagy related 10; PSMA8: Proteasome 20S subunit alpha 8; PSMB2: Proteasome 20S subunit beta 2; USP17L2: Ubiquitin specific peptidase 17 like family member 2; USP8: Ubiquitin specific peptidase 8.

Citation: Li H, Ma YP, Wang HL, Tian CJ, Guo YX, Zhang HB, Liu XM, Liu PF. Establishment of a prognosis predictive model for liver cancer based on expression of genes involved in the ubiquitin-proteasome pathway. World J Clin Oncol 2024; 15(3): 434-446
URL: https://www.wjgnet.com/2218-4333/full/v15/i3/434.htm
DOI: https://dx.doi.org/10.5306/wjco.v15.i3.434