Prevalence, risk factors, and BRAF mutation of colorectal sessile serrated lesions among Vietnamese patients

doi:10.5306/wjco.v15.i2.290

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World Journal of Clinical Oncology

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Feb 24, 2024; 15(2): 290-301
Published online Feb 24, 2024. doi: 10.5306/wjco.v15.i2.290

Table 1 Characteristics of participants, n (%)

Characteristics	Total (n = 1585)	No polyp (n = 1480)	SSLs (n = 105)	P value¹
Sex
Male	657 (41.5)	593 (40.1)	64 (61)	< 0.001
Female	928 (58.5)	887 (59.9)	41 (39)	< 0.001
Age
< 40	402 (25.4)	393 (26.6)	9 (8.6)
40-49	378 (23.8)	364 (24.6)	14 (13.3)	0.232
50-59	437 (27.6)	402 (27.2)	35 (33.3)	< 0.001
60-69	283 (17.9)	253 (17.1)	30 (28.6)	< 0.001
≥ 70	85 (5.4)	68 (4.6)	17 (16.2)	< 0.001
Obesity
Yes	296 (18.7)	271 (18.3)	25 (23.8)	0.162
No	1289 (81.3)	1209 (81.7)	80 (76.2)	0.162
Smoking
Yes/ever	300 (18.9)	262 (17.7)	38 (36.2)	< 0.001
No	1285 (81.1)	1218 (82.3)	67 (63.8)	< 0.001
Alcohol consumption
Yes	189 (11.9)	169 (11.4)	20 (19)	0.020
No	1396 (88.1)	1311 (88.6)	85 (81)	0.020
Hypertension
Yes	307 (19.4)	272 (18.4)	35 (33.3)	< 0.001
No	1278 (80.6)	1208 (81.6)	70 (66.7)	< 0.001
Diabetes mellitus
Yes	113 (7.1)	93 (6.3)	20 (19)	< 0.001
No	1472 (92.9)	1387 (93.7)	85 (81)	< 0.001
Family history of CRC
Yes	100 (6.8)	100 (6.8)	7 (6.7)	0.972
No	1478 (93.2)	1380 (93.2)	98 (93.3)	0.972

¹Comparison between groups with sessile serrated lesions and no polyps. CRC: Colorectal cancer; OR: Odd ratio; CI: confidence interval; SSLs: Sessile serrated lesions.

Citation: Vu NTH, Le HM, Vo DTN, Vu HA, Le NQ, Ho DDQ, Quach DT. Prevalence, risk factors, and BRAF mutation of colorectal sessile serrated lesions among Vietnamese patients. World J Clin Oncol 2024; 15(2): 290-301
URL: https://www.wjgnet.com/2218-4333/full/v15/i2/290.htm
DOI: https://dx.doi.org/10.5306/wjco.v15.i2.290