Germline pathogenic variants among high hereditary risk patients with breast and ovarian cancer and unaffected subjects in Lebanese Arab women

Table 4 Sequence mutations identified in patients with germline pathogenic variants other than breast cancer susceptibility gene 1/2 (all 3 patients were diagnosed with breast cancer)

Genes	Nucleotide change	Molecular consequence	Location	Number of patients
PALB2	C.2257C>T	P.Arg753Ter	Exon 5	1
PALB2	C.93dupA	P.Leu32fs	Exon 2	1
Tumor protein p53	C.375G>A	P.(Thr125)	Exon 4	1

PALB2: Partner and localizer of breast cancer susceptibility gene 2.