Retrospective Study
Copyright ©The Author(s) 2024.
World J Clin Oncol. Dec 24, 2024; 15(12): 1481-1490
Published online Dec 24, 2024. doi: 10.5306/wjco.v15.i12.1481
Table 2 Breast cancer susceptibility gene 2 pathogenic variants identified in patients with breast/ovarian cancer
Nucleotide change
Molecular consequence
Location
Number of patients
Breast cancer
C.9257-1G>ASplice acceptorIntron 243
C.3189_3192delP.Ser1064fsExon 111
C.2808_2811delP.Ala938fsExon 111
Ovarian cancer
C.9257-1G>ASplice acceptorIntron 241
C.7806-2A>TSplice acceptorIntron 161