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©The Author(s) 2024.
World J Clin Oncol. Dec 24, 2024; 15(12): 1481-1490
Published online Dec 24, 2024. doi: 10.5306/wjco.v15.i12.1481
Published online Dec 24, 2024. doi: 10.5306/wjco.v15.i12.1481
Table 2 Breast cancer susceptibility gene 2 pathogenic variants identified in patients with breast/ovarian cancer
Nucleotide change | Molecular consequence | Location | Number of patients |
Breast cancer | |||
C.9257-1G>A | Splice acceptor | Intron 24 | 3 |
C.3189_3192del | P.Ser1064fs | Exon 11 | 1 |
C.2808_2811del | P.Ala938fs | Exon 11 | 1 |
Ovarian cancer | |||
C.9257-1G>A | Splice acceptor | Intron 24 | 1 |
C.7806-2A>T | Splice acceptor | Intron 16 | 1 |
- Citation: Moukadem HA, Fakhreddine MA, Assaf N, Safi N, Al Masry A, Al Darazi M, Mahfouz R, El Saghir NS. Germline pathogenic variants among high hereditary risk patients with breast and ovarian cancer and unaffected subjects in Lebanese Arab women. World J Clin Oncol 2024; 15(12): 1481-1490
- URL: https://www.wjgnet.com/2218-4333/full/v15/i12/1481.htm
- DOI: https://dx.doi.org/10.5306/wjco.v15.i12.1481