Whole exome sequencing identifies risk variants associated with intracranial epidermoid cyst deterioration: A case report

Figure 2 Bioinformatics analyses of the two risk variants. A: Analysis of the conservation of Gap junction protein beta 2 (GJB2): P86Thr and Toll-like receptor 2 (TLR2): P347Lys across species; B: Local depictions of the three-dimensional protein structure of GJB2 prior to and after mutation; C: Local depictions of the three-dimensional protein structure of TLR2 prior to and after mutation. Black boxes indicate the altered amino acid. GJB2: Gap junction protein beta 2; TLR2: Toll-like receptor 2.