Potential regulatory mechanism and clinical significance of synaptotagmin binding cytoplasmic RNA interacting protein in colorectal cancer

Figure 7 The regulatory mechanism of synaptotagmin binding cytoplasmic RNA interacting protein mRNA in colorectal cancer were explored based on assay for transposase-accessible chromatin-seq and chromatin immunoprecipitation-seq. A: Assay for transposase-accessible chromatin-seq showed the prominent enrichment in the promotor region of synaptotagmin binding cytoplasmic RNA interacting protein mRNA (SYNCRIP). And the promotor region of SYNCRIP were also enriched in chromatin immunoprecipitation-seq (ChIP-seq) with H3K4me1 and H3K27ac marked samples; B: In the POLR2A marked ChIP-seq data, the promotor region of SYNCRIP were also enriched and SYNCRIP might be regulated by POLR2A.