Basic Study
Copyright ©The Author(s) 2024.
World J Clin Oncol. Oct 24, 2024; 15(10): 1293-1308
Published online Oct 24, 2024. doi: 10.5306/wjco.v15.i10.1293
Table 4 mRNA expression content in the phosphoinositide 3-kinase/protein kinase B signaling pathway (mean ± SD)
Group
EGFR
PIK3CA
AKT1
IL6
BCL2
Model1.00 ± 0.10.80 ± 0.251.01 ± 0.111.56 ± 0.062.23 ± 0.52
Capecitabine0.97 ± 0.40.34 ± 0.17a0.07 ± 0.04b1.01 ± 0.14b0.52 ± 0.13b
BXD0.79 ± 0.39a0.41 ± 0.180.04 ± 0.01b1.52 ± 0.251.09 ± 0.56a
LY2940020.25 ± 0.14b0.07 ± 0.02b0.09 ± 0.05b1.59 ± 0.170.85 ± 0.47a
BXD + LY2940020.01 ± 0.01b0.38 ± 0.210.06 ± 0.01b0.74 ± 0.07b0.40 ± 0.11b