Identification of the key genes and mechanisms associated with transcatheter arterial chemoembolisation refractoriness in hepatocellular carcinoma

Figure 11  Single-cell RNA sequencing analysis and AUCell. A: Uniform manifold approximation and projection (UMAP) plot showing four cell types in hepatocellular carcinoma samples; B: Violin plots showing the expression level of five key genes in four cell types. C: Expression level of five key genes in four cell types were drawn on UMAP; D: AUCell score distribution curves of 112 transcatheter arterial chemoembolisation (TACE) refractoriness-related genes; E: Scatter plot showing the distribution of AUCell scores in 112 TACE refractoriness-related genes. DLGAP5: DLG associated protein 5; KIF20A: Kinesin family member 20A; ASPM: Assembly factor for spindle microtubules; KIF11: Kinesin family member 11; TPX2: TPX2 microtubule nucleation factor; AUC: Area under the curve.