Scinderin promotes glioma cell migration and invasion via remodeling actin cytoskeleton

Figure 5 Inhibition of RhoA-focal adhesion kinase signaling reverses scinderin -mediated malignant behaviors in glioma cells. A: Effects of PF-573228 and Y-27632 on the migration of U87 and U251 cells, evaluated by wound healing assay; B: Transwell assay with Matrigel was performed to examine the invasion property. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001 vs the Vector groups; ^dP < 0.05, ^eP < 0.01, ^fP < 0.001 vs the SCIN_OE groups.