Scinderin promotes glioma cell migration and invasion via remodeling actin cytoskeleton

Figure 3 Scinderin silencing inhibits glioma cell malignant behaviors. A: Cell proliferation was assessed using the Cell Counting Kit-8; B: U87 and U251 cells were transfected with scinderin (SCIN) short hairpin RNAs (shRNAs) to determine cell proliferation by colony formation assay; C: Effect of downregulated SCIN on the migration of U87 and U251 was evaluated by a wound-healing assay. Scale bar = 100 μm; D: Transwell assay with Matrigel was performed to examine the invasion property. ^bP < 0.01, ^cP < 0.001.