Clinical and Translational Research
Copyright ©The Author(s) 2024.
World J Clin Oncol. Jan 24, 2024; 15(1): 45-61
Published online Jan 24, 2024. doi: 10.5306/wjco.v15.i1.45
Table 2 The COX regression analysis about clinicopathological characteristics associated with the survival of lung adenocarcinoma patients
CharacteristicsTotal (N)Univariate analysis
Multivariate analysis
Hazard ratio (95%CI)
P value
Hazard ratio (95%CI)
P value
Pathologic T stage527
T1176Reference Reference
T22851.507 (1.059-2.146)0.0231.086 (0.726-1.624)0.687
T3 & T4663.095 (1.967-4.868)< 0.0011.571 (0.827-2.984)0.168
Pathologic N stage514
N0345Reference Reference
N1962.293 (1.632-3.221)< 0.0011.293 (0.653-2.560)0.461
N2 & N3732.993 (2.057-4.354)< 0.0011.774 (0.906-3.471)0.094
Pathologic stage522
Stage I292Reference Reference
Stage II & stage III & stage IV2302.889 (2.141-3.897)< 0.0011.587 (0.789-3.193)0.195
Age520
≤ 65257Reference
> 652631.216 (0.910-1.625)0.186
Gender530
Female283Reference
Male2471.087 (0.816-1.448)0.569
Number pack years smoked363
< 40183Reference
≥ 401801.073 (0.753-1.528)0.697
HSPA4530
Low266Reference Reference
High2641.476 (1.104-1.972)0.0091.356 (0.967-1.901)0.078