Advances in drug resistance of triple negative breast cancer caused by pregnane X receptor

doi:10.5306/wjco.v14.i9.335

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Sep 24, 2023 (publication date) through Jul 17, 2024

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Sep 24, 2023; 14(9): 335-342
Published online Sep 24, 2023. doi: 10.5306/wjco.v14.i9.335

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Figure 1 Three phases in the chemotherapy drug resistance mechanism caused by pregnane X receptor in triple-negative breast cancer. RXR: Retinal X receptor; PXR: Pregnane X receptor; ABC: Adenosine triphosphate binding cassette; CYPs: Cytochrome P450s; UGTs: Uridine diphosphate glucuronosyltransferase; GSTs: Glutathione transferase.

Citation: Rao ZZ, Tang ZW, Wen J. Advances in drug resistance of triple negative breast cancer caused by pregnane X receptor. World J Clin Oncol 2023; 14(9): 335-342
URL: https://www.wjgnet.com/2218-4333/full/v14/i9/335.htm
DOI: https://dx.doi.org/10.5306/wjco.v14.i9.335