Immune microenvironment of medulloblastoma: The association between its molecular subgroups and potential targeted immunotherapeutic receptors

Figure 3 The signaling interaction between tumour cells, tumor-associated macrophages, and tumour infiltrating lymphocytes in medulloblastoma microenvironment. Tumour microenvironment represents diverse cellular heterogeneities including immune and none-immune cells. The targeted receptors linked between immune cells represent a potential targeted therapy. CAF: Cancer-associated fibroblasts; MB: Medulloblastoma; NK: Natural killer; TAM: Tumor-associated macrophage; TIL: Tumour infiltrating lymphocytes.