Significance of serum carcinoembryonic antigen in metastatic breast cancer patients: A prospective study

Table 3 Serum carcinoembryonic antigen and response to treatment in responders and non-responders according to breast cancer type

Classification		Responders			Non-responders
		Median pre-CEA	Median post-CEA	P value	Median pre-CEA	Median post-CEA	P value
Hormonal classification	Luminal	14.7 (5.4-50.6)	3 (1-10)	0.001	22.39 (3.9-84.4)	21.00 (10.6-164.15)	0.26
	Non-luminal	1.85 (1-3.65)	1.25 (0.5-3)	0.046	4.15 (0.85-10.17)	5.65 (2.65-12.05)	0.161
Genomic classification	Luminal	14.7 (5.4-50.6)	3 (1-10)	0.001	22.39 (3.9-84.47)	20.67 (10.6-164.17)	0.260
	HER2	4 (1.2-4)	3.25 (0.5-3.25)	0.18	11.7	13	_
	TNBC	1.85 (0.74-2.4)	1.25 (0.67-1.88)	0.144	4 (0.5-5.6)	5.3 (2.2-9.2)	0.237

TNBC: Triple negative breast cancer; CEA: Carcinoembryonic antigen.