Tumor specifically internalizing peptide ‘HN-1’: Targeting the putative receptor retinoblastoma-regulated discoidin domain receptor 1 involved in metastasis

doi:10.5306/wjco.v13.i5.323

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May 24, 2022 (publication date) through Nov 22, 2024

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. May 24, 2022; 13(5): 323-338
Published online May 24, 2022. doi: 10.5306/wjco.v13.i5.323

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Figure 2 Discoidin domain receptor 1 may mediate HN-1 endocytosis. Discoidin domain receptor 1 (DDR1) protein is upregulated in human head and neck squamous cell carcinoma. Immunohistochemical analysis of DDR1 was conducted by comparing tumor vs normal tissues in Human Protein Atlas database (http://www.proteinatlas.org/). The results showed positive cytoplasmic and membranous staining. Bar: 25 micrometers; DDR1: Discoidin domain receptor 1.

Citation: Hong FU, Castro M, Linse K. Tumor specifically internalizing peptide ‘HN-1’: Targeting the putative receptor retinoblastoma-regulated discoidin domain receptor 1 involved in metastasis. World J Clin Oncol 2022; 13(5): 323-338
URL: https://www.wjgnet.com/2218-4333/full/v13/i5/323.htm
DOI: https://dx.doi.org/10.5306/wjco.v13.i5.323