New horizons for uncommon mutations in non-small cell lung cancer: BRAF, KRAS, RET, MET, NTRK, HER2

doi:10.5306/wjco.v13.i4.276

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 13, Issue 4

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (5167)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Tables (1-5) series.

Item

Count

PDF

389

WORD

HTML

2771

Tables (1-5)

271

Sum=3511

Featured Article

The chart showing Browse series, Download series.

Item

Count

Browse

229

Download

521

Sum=750

Publishing Process of This Article

Item

Count

Browse

303

Download

603

Sum=906

Apr 24, 2022 (publication date) through Oct 3, 2024

Times Cited of This Article

Times Cited (7)

Journal Information of This Article

Publication Name

World Journal of Clinical Oncology

ISSN

2218-4333

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Minireviews

World J Clin Oncol. Apr 24, 2022; 13(4): 276-286
Published online Apr 24, 2022. doi: 10.5306/wjco.v13.i4.276

Table 1 Phase II trials with BRAF inhibitors

Drug	n	ORR (%)	PFS (mo)	OS (mo)
Vemurafenib BRAF V600E[8]	62	37.1	6.51	15.38
Vemurafenib V600E[9]	101	0	5.2	10
Vemurafenib non-V600E[9]	17	44.9	NR	NR
Dabrafenib in 2^nd line or beyond[10]	78	33.3	5.5	12.7
Dabrafenib + trametinib in 2^nd line or beyond[11]	57	63.2	10.2	18.2
Dabrafenib + trametinib en 1^st line[12]	36	64	10.9	24.6

ORR: Overall response rate; PFS: Progression free survival; OS: Overall survival; NR: Not reported.

Citation: Olmedo ME, Cervera R, Cabezon-Gutierrez L, Lage Y, Corral de la Fuente E, Gómez Rueda A, Mielgo-Rubio X, Trujillo JC, Couñago F. New horizons for uncommon mutations in non-small cell lung cancer: BRAF, KRAS, RET, MET, NTRK, HER2. World J Clin Oncol 2022; 13(4): 276-286
URL: https://www.wjgnet.com/2218-4333/full/v13/i4/276.htm
DOI: https://dx.doi.org/10.5306/wjco.v13.i4.276