Systems biology and OMIC data integration to understand gastrointestinal cancers

doi:10.5306/wjco.v13.i10.762

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Oct 24, 2022 (publication date) through Jul 29, 2024

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Oct 24, 2022; 13(10): 762-778
Published online Oct 24, 2022. doi: 10.5306/wjco.v13.i10.762

Table 2 Pathways enriched in transcriptional analyses in esophageal, gastric, liver, pancreas, and colorectal cancers

Pathway	CRC	EC	GC	HCC	PDAC	Ref.
Focal adhesion	X	X	X	X	X	[69-76]
Apoptosis	X	X	X	X	X	[71,72,77-79]
PAK pathway	X	X		X	X	[80-83]
PI3K/Akt signaling pathway	X	X	X			[71,84-86]
TGF-beta pathway		X	X	X	X	[75,76,87-90]
Toll-like receptor signaling pathway		X	X	X		[88,91-93]

CRC: Colorectal cancer; EC: Esophageal cancer; GC: Gastric cancer; HCC: Hepatocellular carcinoma; PAK: p21-activated kinase; PDAC: Pancreatic ductal adenocarcinoma; PI3K: Phosphoinositide 3-kinase; TGF: Transforming growth factor beta.

Citation: Bispo IMC, Granger HP, Almeida PP, Nishiyama PB, de Freitas LM. Systems biology and OMIC data integration to understand gastrointestinal cancers. World J Clin Oncol 2022; 13(10): 762-778
URL: https://www.wjgnet.com/2218-4333/full/v13/i10/762.htm
DOI: https://dx.doi.org/10.5306/wjco.v13.i10.762