Association of cancer with comorbid inflammatory conditions and treatment in patients with Lynch syndrome

Table 3 Distribution of cancers based on genetic diagnosis by comorbid inflammatory condition status

	CID present			CID non present
	CRC	LS specific1	All other	CRC	LS specific	All other
MLH1	2 (40.0)	2 (40.0)	1 (20.0)	2 (20.0)	2 (20.0)	0 (0)
MSH2	2 (66.7)	0 (0)	1 (33.3)	2 (28.6)	4 (57.1)	1 (14.3)
MSH6	0 (0)	0 (0)	0 (0)	2 (50.0)	1 (25.0)	0 (0)
PMS2	2 (50.0)	0 (0)	1 (25.0)	0 (0)	2 (25.0)	0 (0)
No MMRPV	3 (42.9)	1 (14.3)	1 (14.3)	6 (42.9)	1 (7.1)	0 (0)

¹LS Specific cancers other than colorectal cancer. These include endometrial, small bowel and urothelial.

CRC: Colorectal cancer; LS: Lynch syndrome; CID: Comorbid inflammatory condition.