Role of mammogram and ultrasound imaging in predicting breast cancer subtypes in screening and symptomatic patients

Table 2 Distribution of demographic and imaging parameters based on molecular subtype

	Total (n = 328)	DCIS (n = 53)	Luminal A (n = 139)	Luminal B (n = 38)	Her2 enriched (n = 50)	Triple negative (n = 48)
Mean age	61.1 ± 11.75	59.1 ± 11.67	61.8 ± 11.80	60.2 ± 12.23	62.0 ± 9.63	61.3 ± 12.60
Presentation
Clinic	237 (72%)	29 (55%)	98 (71%)	28 (74%)	36 (72%)	46 (96%)
Screening	91 (28%)	24 (45%)	41 (29%)	10 (26%)	14 (28%)	2 (4%)
Mass	200 (61%)	14 (26%)	91 (65%)	29 (76%)	29 (58%)	37 (77%)
Architectural distortion	17 (6%)	7 (13%)	10 (7%)	0 (0%)	0 (0%)	0 (0%)
Asymmetry	40 (12%)	6 (11%)	16 (12%)	3 (8%)	9 (18%)	6 (13%)
High-risk microcalcifications	105 (32%)	27 (51%)	33 (24%)	12 (32%)	24 (48%)	9 (19%)
Tumor size (on USG)
< 20	136 (41%)	22 (42%)	71 (51%)	20 (53%)	19 (38%)	4 (8%)
≥ 20	154 (47%)	9 (17%)	55 (40%)	17 (45%)	29 (58%)	44 (92%)
Margins (on USG)
Spiculated	100 (30%)	5 (9%)	63 (45%)	12 (32%)	8 (16%)	8 (17%)
Microlobulated	174 (60%)	23 (43%)	59 (42%)	25 (66%)	40 (80%)	29 (60%)
Circumscribed	16 (5%)	3 (6%)	4 (3%)	0 (0%)	0 (0%)	11 (23%)
Echogenicity (on USG)
Heterogeneous	144 (44%)	13 (25%)	58 (42%)	19 (50%)	28 (56%)	26 (54%)
Homogenous	146 (45%)	18 (34%)	68 (49%)	18 (47%)	20 (40%)	22 (46%)
Posterior acoustic features
Shadow	74 (23%)	5 (9%)	49 (35%)	10 (26%)	4 (8%)	6 (13%)
Enhancement	85 (26%)	5 (9%)	23 (17%)	8 (21%)	6 (32%)	33 (69%)
Mixed	36 (11%)	5 (9%)	15 (11%)	3 (8%)	9 (18%)	4 (8%)
None	95 (29%)	16 (30%)	39 (28%)	16 (42%)	19 (38%)	5 (10%)
Adler’s vascularity
High (Grade II & III)	81 (25%)	7 (13%)	22 (16%)	11 (29%)	21 (42%)	20 (42%)
Low (Grade I)	209 (64%)	24 (45%)	104 (75%)	26 (68%)	27 (54%)	28 (58%)
Axillary nodes
Present	56 (17%)	0 (0%)	25 (18%)	1 (3%)	14 (28%)	16 (33%)
Absent	234 (71%)	53 (100%)	101 (73%)	36 (95%)	34 (68%)	32 (67%)
Not visible on US	38 (14%)	22 (42%)	13 (9%)	1 (3%)	2 (1%)	0 (0%)

DCIS: Ductal carcinoma in situ; US: Ultrasound; USG: Ultrasonography.