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©The Author(s) 2021.
World J Clin Oncol. Jul 24, 2021; 12(7): 557-564
Published online Jul 24, 2021. doi: 10.5306/wjco.v12.i7.557
Published online Jul 24, 2021. doi: 10.5306/wjco.v12.i7.557
Table 2 Potential advantages (+) and disadvantages (-) of preoperative chemoradiation and perioperative chemotherapy
| Preoperative chemoradiotherapy | Perioperative chemotherapy |
| + Better loco-regional control | + Better systemic control |
| + High rates of complete pathologic response | + No adverse events from radiotherapy |
| - Poorer response in adenocarcinoma (increased radiation sensitivity in squamous cell carcinoma) | - Poorer loco-regional control |
| - Radiation-induced changes in surgical field | - Many patients are not able to complete the postoperative regimen |
- Citation: Laxague F, Schlottmann F. Esophagogastric junction adenocarcinoma: Preoperative chemoradiation or perioperative chemotherapy? World J Clin Oncol 2021; 12(7): 557-564
- URL: https://www.wjgnet.com/2218-4333/full/v12/i7/557.htm
- DOI: https://dx.doi.org/10.5306/wjco.v12.i7.557