Copyright
©The Author(s) 2021.
World J Clin Oncol. Jun 24, 2021; 12(6): 458-467
Published online Jun 24, 2021. doi: 10.5306/wjco.v12.i6.458
Published online Jun 24, 2021. doi: 10.5306/wjco.v12.i6.458
Table 1 Incidence of chemotherapy-induced peripheral neuropathy
Trail | Indication | No. of patients | Treatment | Grade 1 (%) | Grade 2 (%) | Grade 3 (%) |
AGO OVAR 3[35] | FIGO IIB-IV fist line | 388 | CP | 39 | 28 | 6.7 |
384 | PP | 33 | 36 | 12.5 | ||
JGOG[29] | FIGO II-IV fist line | 319 | CP | 20 (6) | ||
312 | C-P | 21 (7) | ||||
MITO 4[27] | FIGO IC-IV fist line | 120 | CP | 51 (42) | 13 (11) | 1 (1) |
MITO 2[26] | FIGO IC-IV fist line | 407 | CP | 115 (28) | 64 (16) | 12 (3) |
396 | C-PLD | 47 (12) | 11 (3) | 1 (< 1) | ||
MITO 7[28] | FIGO IC-IV fist line | 404 | CP | 95 (24) | 58 (15) | 8 (2) |
406 | CP weekly | 98 (25) | 24 (6) | 0 | ||
ICON 4[2] | Platinum-sensitive relapse > 6 mo | 410 | P-based | 4 (1) | ||
392 | CP/PP | 76 (20) |
- Citation: Oneda E, Abeni C, Zanotti L, Zaina E, Bighè S, Zaniboni A. Chemotherapy-induced neurotoxicity in the treatment of gynecological cancers: State of art and an innovative approach for prevention. World J Clin Oncol 2021; 12(6): 458-467
- URL: https://www.wjgnet.com/2218-4333/full/v12/i6/458.htm
- DOI: https://dx.doi.org/10.5306/wjco.v12.i6.458