Immune response evaluation criteria in solid tumors for assessment of atypical responses after immunotherapy

Figure 2 Axial computed tomography images in the portal-venous phase of a 69 y/o male, ex-smoker with non-small lung cell carcinoma, during second-line therapy with Atezolizumab. A: Pre-treatment imaging show the right peri-hilar lesion; B: During follow-up after 4 wk the lesion increase in size; C and D: During the following computed tomography scans (8 and 12 wk) a significant decrease in longest diameter was achieved, confirming a final response to treatment with the presence of intercurrent (B) pseudoprogression.