Cytotoxic CD8+ T cells and tissue resident memory cells in colorectal cancer based on microsatellite instability and BRAF status

Figure 2 Programmed cell death protein-1 expression on CD8+ T cells is not impacted by microsatellite instability or BRAF status. Quantitative immunohistochemistry staining was used to determine the expression of programmed cell death protein-1 (PD-1) on CD8+ T cell populations. Figure shows the proportion of total CD8+ T cells (CD8+CD103+/-) (left panel), CD103-CD8+ (non-T_RM) T cells (middle panel) and CD103+CD8+ T_RM cells (right panel) expressing PD-1. Figure shows the mean and SD for 5-6 samples/group. PD-1: Programmed death 1; MSS: Microsatellite stable; MSI-H: High microsatellite instability.