Positron emission tomography complete metabolic response as a favorable prognostic predictor in esophageal cancer following neoadjuvant chemotherapy with docetaxel/cisplatin/5-fluorouracil

doi:10.5306/wjco.v12.i4.249

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World Journal of Clinical Oncology

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World J Clin Oncol. Apr 24, 2021; 12(4): 249-261
Published online Apr 24, 2021. doi: 10.5306/wjco.v12.i4.249

Table 7 Univariable and multivariable analyses of prognostic factors in esophageal cancer

	Overall survival
	Univariate			Multivariate
	RR	95%CI	P value	RR	95%CI	P value
Age	1.036	0.972-1.112	0.285
Male/Female	1.302	0.204-4.683	0.736
Location, MtLtAe/CeUt	1.057	0.242-3.291	0.931
Tumor grade, other/por	1.603	0.499-4.466	0.403
0▪1▪2/3▪4	8.167	2.912-25.340	< 0.0001	1.644	0.430-8.039	0.486
pN, 0/1▪2▪3	5.653	1.803-24.800	0.0021	0.924	0.045-7.556	0.946
pM, 0/1	5.043	1.354-15.690	0.019	1.518	0.302-6.353	0.588
pStage, 0▪1▪2/3▪4	15.52	5.062-58.400	< 0.0001	5.760	0.415-160.800	0.197
pCR (primary tumor), CR (+)/nonCR (-)	3.202	0.887-20.470	0.0793
CT-PET-T, (-)/(+)	3.227	1.106-11.680	0.0313	1.450	0.307-6.866	0.630
CT-PET-N, (-)/(+)	25.270	6.361-168.100	< 0.0001	8.268	1.748-63.630	0.006
CT-PET-CMR, (-)/(+)	2.927	0.996-10.660	0.0510

Ae: Abdominal esophagus; Ce: Cervical esophagus; CI: Confidence interval; CR: Complete response; CT-PET-N: Computed tomography-positron emission tomography negative N; CT-PET-T: Computed tomography-positron emission tomography negative T; Lt: Lower thoracic esophagus; Mt: Middle thoracic esophagus; pCR: Pathological complete response; PET-CMR: Positron emission tomography-complete metabolic response; por: Poorly differentiated carcinoma; RR: Relative risk; Ut: Upper thoracic esophagus.

Citation: Suzuki K, Etoh T, Shibata T, Nishiki K, Fumoto S, Ueda Y, Shiroshita H, Shiraishi N, Inomata M. Positron emission tomography complete metabolic response as a favorable prognostic predictor in esophageal cancer following neoadjuvant chemotherapy with docetaxel/cisplatin/5-fluorouracil. World J Clin Oncol 2021; 12(4): 249-261
URL: https://www.wjgnet.com/2218-4333/full/v12/i4/249.htm
DOI: https://dx.doi.org/10.5306/wjco.v12.i4.249