GOECP/SEOR radiotherapy guidelines for thymic epithelial tumours

Table 7 Constraints to the main organs

Organ	Constraints
Spinal cord	Dmax < 45 Gy
	Dmax < 40 Gy if 3 Gy/fraction
Lung (total lung minus GTV; solely total lung for postoperative cases without GTV)	Mean dose < 20 Gy
	Mean dose < 8 Gy if post-pneumonectomy
	RT alone	RT with chemotherapy	Neoadjuvant treatment before surgery
	V20 ≤ 40%	V20 ≤ 35%	V20 ≤ 30%
		V10 ≤ 45%	V10 ≤ 40%
		V5 ≤ 65%	V5 ≤ 55%
	V20 < 10% and V5 < 60% if post-pneumonectomy
Heart	Mean dose < 26 Gy
	V30 ≤ 45%
Esophagus	Mean dose < 34 Gy
	Dmax ≤ 80 Gy
	V70 < 20%
	V50 < 50%
Kidney	20 Gy < 32% bilateral kidney
Liver	Mean dose < 30 Gy
	V30 ≤ 40%

GTV: Gross tumour volume; RT: Radiotherapy.