Guidelines
Copyright ©The Author(s) 2021.
World J Clin Oncol. Mar 24, 2021; 12(3): 115-143
Published online Mar 24, 2021. doi: 10.5306/wjco.v12.i3.115
Table 3 Tumor-node-metastasis American Joint Committee on Cancer 8th edition lung cancer
TNM AJCC 8th edition lung cancer
T: Primary tumour
TxNot evaluable by imaging or malignant cells in sputum or bronchial lavage
T0No evidence of primary tumour
TisCarcinoma in situ
T1≤ 3 cm surrounded by lung or visceral pleura, or lobar bronchus
T1a (mi)Minimally invasive
T1a≤ 1 cm
T1b> 1 cm to ≤ 2 cm
T1c> 2 cm to ≤ 3 cm
T2> 3 cm to ≤ 5 cm, or involving main bronchus without affecting the carina, visceral pleura, or atelectasis or obstructive pneumonitis extending to the hilar region, affecting part or all of the lung
T2a> 3 cm to ≤ 4 cm
T2b> 4 cm to ≤ 5 cm
T3> 5 cm to ≤ 7 cm, or tumour nodules in the same lobe, or invasion of the chest wall (parietal pleura), phrenic nerve, parietal pericardium
T4> 7 cm, or nodules in a different ipsilateral lobe or invasion of the diaphragm, mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, and carina
N: Regional lymph node involvement
NxNot evaluable
N0No node involvement
N1Ipsilateral peribronchial and/or hilar and intrapulmonary nodes
N2Ipsilateral mediastinal nodes and/or subcarinal
N3Contralateral mediastinal or contralateral hilar nodes, or any scalene or supraclavicular nodes
M: Distant metastasis
M0No metastasis
M1Distant metastasis
M1aNodules in contralateral lobe; pleural or pericardial or pleural or pericardial effusion
M1bSingle extrathoracic metastasis (including non-regional lymph node)
M1cMultiple extrathoracic metastases