Real-world evaluation of upfront docetaxel in metastatic castration-sensitive prostate cancer

Table 4 Progression-free survival (according to Swedish national guidelines) age, PSA, comorbidities and bone metastases

	Number of patients	Number of events	HR, 95%CI, P value (univariate)	HR, 95%CI, P value (multivariate)
Age, yr (median)
≤ 68	48	22	1.00	1.00
> 68	46	17	0.83, 0.44-1.56, 0.55	0.88, 0.46-1.71, 0.71
PSA (median)
≤ 180	48	13	1.00	1.00
> 180	46	26	2.86, 1.44-5.69, 0.0028	2.57, 1.28-5.16, 0.0081
Comorbidities
No	44	17	1.00	1.00
Yes	50	22	1.06, 0.56-2.00, 0.85	1.08, 0.56-2.07, 0.83
Distant metastases
No	19	4	1.00	1.00
Yes	75	35	2.69, 0.96-7.59, 0.061	2.11, 0.73-6.06, 0.17