Novel molecular panel for evaluating systemic inflammation and survival in therapy naïve glioma patients

Table 5 Difference in preoperative and postoperative concentrations of markers in blood samples collected in a 3-mo follow-up

No	Markers	Preoperative concentration	3-mo postoperative concentration	P value	rs value
1	KYN (ng/mL)	126.1 (19.410-387.440)	75.405 (16.340-227.400)	0.0148a	0.4509
2	IL-6 (pg/mL)	75.65 (23.96-209.73)	60.03 (21.85-140.77)	0.0107a	0.1850
3	NLR	4.30 (1.43-15.00)	2.93 (0.80-6.90)	0.0038b	0.7260
4	hTERT (ng/L)	2.27 (1.16-6.86)	1.33 (0.78-4.78)	0.0016b	0.6574

^aP < 0.05.

^bP < 0.01.

Concentration presented as median with ranges. hTERT: Human telomerase reverse transcriptase; IL-6: Interleukin-6; KYN: Kynurenine; NLR: Neutrophil-lymphocytes ratio.