Evidence Review
Copyright ©The Author(s) 2021.
World J Clin Oncol. Oct 24, 2021; 12(10): 833-844
Published online Oct 24, 2021. doi: 10.5306/wjco.v12.i10.833
Table 1 Recommendations for postoperative radiotherapy according to the main international guidelines
GuidelinesClinical scenarioRecommendation for PORT
NCCN[9]Stage pN0-1 Not recommended
Stage pN2, negative surgical margins (R0)Sequential
Microscopic or macroscopic surgical margins (R1-R2)Concomitant (selected cases) or sequential
ASTRO[10]Stage pN2 Sequential
Microscopic or macroscopic surgical margins (R1-R2)Concomitant (selected cases) or sequential
ESTRO-ASTRO[11]
Multiple nodal stations involvedSequential
Extracapsular nodal extensionSequential
ESMO[12]Early stage (I-II) disease (R0) Not recommended
Positive margins or chest wall involvement (R1-R2)Sequential
Stage pN2Only in selected cases
ASCO[13]Early stage (I-II) disease (R0) Not recommended
Stage pN2Only in selected cases