Evolutionary model of brain tumor circulating cells: Cellular galaxy

Figure 6 Status of protein expression of C-C chemokine ligand 2, vascular endothelial growth factor, and epidermal growth factor in the tumor and circulating tumor cells of patient 4 affected with meningioma. C-C chemokine ligand 2 (CCL2), vascular endothelial growth factor (VEGF), and epidermal growth factor (EGF) are conjugated with fluorescein isothiocyanate, R-phycoerythrin, and phycoerythrin–indodicarbocyanine, respectively, in patient number 2. A1-4: 4′,6-Diamidino-2-phenylindole, CCL2, VEGF, EGF; B1-5: CCL2, VEGF, EGF, co-expression of CCL2/VEGF/EGF, co-expression of 4′,6-diamidino-2-phenylindole/CCL2/VEGF/EGF, Selected cropping area of image B4, is reflective of diverse co-expression between these three proteins from image B4.