Copyright
©The Author(s) 2021.
World J Clin Oncol. Jan 24, 2021; 12(1): 13-30
Published online Jan 24, 2021. doi: 10.5306/wjco.v12.i1.13
Published online Jan 24, 2021. doi: 10.5306/wjco.v12.i1.13
Figure 4 The harmonic ratio of tumor cells with different degree of expression intensity for protein C-C chemokine ligand 2, vascular endothelial growth factor, and epidermal growth factor to the circulating tumor cells in patients with brain tumors.
C-C chemokine ligand 2 (CCL2), vascular endothelial growth factor (VEGF), and epidermal growth factor (EGF) are conjugated with fluorescein isothiocyanate, R-phycoerythrin, and phycoerythrin–indodicarbocyanine, respectively. The highlighted quadrants with different colors indicate the harmonic evolutionary altered intensity including increased and/or decreased ratio value of the related proteins in common between different patients or within different proteins. The altered ratio is based on the provided data in Figure 1; Numbers 1 (high), 2 (medium) and 3 (low) are reflective of expression intensity of proteins CCL, VEGF and EGF. C: C-C chemokine ligand 2; V: Vascular endothelial growth factor; E: Epidermal growth factor.
- Citation: Mehdipour P, Javan F, Jouibari MF, Khaleghi M, Mehrazin M. Evolutionary model of brain tumor circulating cells: Cellular galaxy. World J Clin Oncol 2021; 12(1): 13-30
- URL: https://www.wjgnet.com/2218-4333/full/v12/i1/13.htm
- DOI: https://dx.doi.org/10.5306/wjco.v12.i1.13