Are all prostate cancer patients "fit" for salvage radiotherapy?

Table 2 Risk groups for salvage radiotherapy

Risk group	Factors
Low-risk	PSA < 0.6 ng
	PSA-DT > 12 mo
	Gleason score ≤ 7 (ISUP 1,2)
	pT2 pN0
	IBR > 18 mo
	Negative margins
Intermediate risk	PSA = 0.6 to < 1 ng
	PSA-DT 6-12 mo
	Gleason score 7 (ISUP 3)
	pT2-T3a pN0 or pNx
	IBR > 18 mo
	Positive margins
High-risk	PSA ≥ 1 ng
	PSA-DT < 6 mo
	Gleason score 8-10 (ISUP 4,5)
	pT3b pN0 or pNx
	IBR < 18 mo
	Positive margins

ADT: Androgen deprivation therapy; PSA: Prostate-specific antigen; PSA-DT: Prostate-specific antigen doubling time; IBR: Interval to biochemical recurrence; ISUP: International Society of Urological Patheology.