Impact of conditioning regimen on peripheral blood hematopoietic cell transplant

doi:10.5306/wjco.v10.i2.86

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Feb 24, 2019; 10(2): 86-97
Published online Feb 24, 2019. doi: 10.5306/wjco.v10.i2.86

Table 3 Time to neutrophil and platelet engraftment by CD34+ dose for each conditioning regimen group

	Conditioning group
	MA-noTBI (n = 38)	MA + TBI (n = 51)	RIC-noTBI (n = 118)	RIC + TBI (n = 40)
	Median days to engraftment (range)
Absolute neutrophil count > 500/mm³
CD34+ dose > 4 × 10⁶/kg	14 (10-22)	14 (9-28)	14 (3-36)	15 (10-22)
CD34+ dose < 4 × 10⁶/kg	14.5 (12-19)	19 (13-28)	15 (10-21)	18 (16-24)
P	NS	NS	NS	0.01
Platelet count > 20000/mm³
CD34+ dose > 4 × 10⁶/kg	17 (3-171)	20 (13-81)	17 (3-1515)	17 (10-866)
CD34+ dose < 4 × 10⁶/kg	19.5 (15-32)	34 (20-228)	22 (14-275)	18 (11-20)
P	NS	0.001	0.01	NS

MA: Myeloablative; TBI: Total body irradiation; RIC: Reduced intensity conditioning; NS: Not significant (P > 0.05).

Citation: Burns M, Singh AK, Hoefer CC, Zhang Y, Wallace PK, Chen GL, Platek A, Winslow TB, Iovoli AJ, Choi C, Ross M, McCarthy PL, Hahn T. Impact of conditioning regimen on peripheral blood hematopoietic cell transplant. World J Clin Oncol 2019; 10(2): 86-97
URL: https://www.wjgnet.com/2218-4333/full/v10/i2/86.htm
DOI: https://dx.doi.org/10.5306/wjco.v10.i2.86