Molecular mechanism of base pairing infidelity during DNA duplication upon one-electron oxidation

Figure 5 As the two strands of the double helix unwind, each pairs up with the appropriate bases to form a new double helix. The two new helices are identical to each other and to the original. This process is compromised by one-electron oxidation of the π-DNA stack, deprotonation from G^•+ and the subsequent formation of G(-H)^•, which is promiscuous with regard to base pairing.