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World J Clin Oncol. Nov 10, 2010; 1(1): 12-17
Published online Nov 10, 2010. doi: 10.5306/wjco.v1.i1.12
Published online Nov 10, 2010. doi: 10.5306/wjco.v1.i1.12
Figure 1 Oxidation of guanine (G) and deprotonation of its radical cation (G•+).
The pKa-value of G is drastically lowered upon one-electron oxidation and subsequent deprotonation of the N1 proton changes it from a hydrogen bond donor to a hydrogen bond acceptor. The number of atoms constituting G is shown. Drib: 2’-deoxyribose moiety.
- Citation: Reynisson J. Molecular mechanism of base pairing infidelity during DNA duplication upon one-electron oxidation. World J Clin Oncol 2010; 1(1): 12-17
- URL: https://www.wjgnet.com/2218-4333/full/v1/i1/12.htm
- DOI: https://dx.doi.org/10.5306/wjco.v1.i1.12