Coeliac disease in the modern era: Severity of small bowel mucosal injury at diagnosis with analysis of clinical correlates and rate of improvement on a gluten free diet

Table 8 Independent predictors of a Marsh-Oberhuber score ≥ 3a after repeat duodenal biopsy, at least 6 mo after diagnosis of coeliac disease for 87 patients

Characteristic	Odds ratio	95%CI	P value
Age below 40 yr	0.59	0.23-1.57	0.292
Female gender	1.13	0.40-3.20	0.824
Gluten free diet	0.03	0.00-0.34	0.004
Symptoms at second biopsy1	0.45	0.81-2.48	0.358
Positive serology at second biopsy	0.64	0.18-2.27	0.485

¹n = 51 patients. CI: Confidence interval.