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©The Author(s) 2018.
World J Gastrointest Pharmacol Ther. Aug 7, 2018; 9(3): 22-30
Published online Aug 7, 2018. doi: 10.4292/wjgpt.v9.i3.22
Published online Aug 7, 2018. doi: 10.4292/wjgpt.v9.i3.22
Table 5 Summary of results of pharmacokinetic variables from analyses-of-variance: Lactulose 10 g (liquid) vs Water
| Liquid | Lactulose 10 g | Water 250 mL | Treatment difference | |||||
| Variable | n | LS mean | 95%CI | n | LS mean | 95%CI | Difference | 95%CI |
| iAUC (mmol/L*min) | 12 | 5.89 | (-8.94; 20.72) | 12 | 9.92 | (-4.92; 24.77) | -4.029 | (-20.97; 12.91) |
| AUC (mmol/L*min) | 12 | 886.19 | (852.75; 919.64) | 12 | 890.45 | (856.97; 923.93) | -4.258 | (-33.36; 24.85) |
| AUC_base (mmol/L*min) | 12 | -53.93 | (-87.38; -20.48) | 12 | -49.67 | (-83.15; -16.19) | -4.258 | (-33.36; 24.85) |
| C_max (mmol/L) | 12 | 5.41 | (5.17; 5.66) | 12 | 5.49 | (5.24; 5.73) | -0.073 | (-0.35; 0.20) |
| Max_increase (mmol/L) | 12 | 0.19 | (-0.05; 0.43) | 12 | 0.26 | (0.02; 0.51) | -0.073 | (-0.35; 0.20) |
- Citation: Steudle J, Schön C, Wargenau M, Pauly L, Schwejda-Güttes S, Gaigg B, Kuchinka-Koch A, Stover JF. Blood glucose response after oral intake of lactulose in healthy volunteers: A randomized, controlled, cross-over study. World J Gastrointest Pharmacol Ther 2018; 9(3): 22-30
- URL: https://www.wjgnet.com/2150-5349/full/v9/i3/22.htm
- DOI: https://dx.doi.org/10.4292/wjgpt.v9.i3.22