Thiol/disulphide homeostasis in celiac disease

doi:10.4292/wjgpt.v8.i2.120

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World Journal of Gastrointestinal Pharmacology and Therapeutics

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World J Gastrointest Pharmacol Ther. May 6, 2017; 8(2): 120-126
Published online May 6, 2017. doi: 10.4292/wjgpt.v8.i2.120

Table 3 Findings related to thiol/disulphide hemostasis parameters in celiac patient group

Variables	Native thiol		Total thiol		Disulphide		Disulphide/total thiol		Disulphide/native thiol		Native thiol/total thiol
Variables	r	P value	r	P value	r	P value	r	P value	r	P value	r	P value
Age	0.261	0.026^a	0.262	0.025^a	-0.041	0.729	-0.132	0.264	-0.122	0.302	0.021	0.861
BMI	0.19	0.107	0.187	0.114	-0.033	0.783	-0.096	0.421	-0.113	0.34	0.045	0.702
Total protein	-0.032	0.786	0.005	0.97	0.059	0.618	0.032	0.787	0.086	0.472	-0.156	0.187
Albumin	0.009	0.937	0.025	0.835	-0.037	0.754	-0.065	0.582	-0.040	0.735	-0.071	0.548
AST	0.051	0.666	0.046	0.702	-0.03	0.801	-0.057	0.631	-0.031	0.796	0.033	0.781
ALT	-0.091	0.444	-0.116	0.329	-0.063	0.598	-0.012	0.919	0.002	0.985	0.094	0.427
CRP	-0.327	0.018^a	-0.304	0.038^a	0.369	0.015^a	0.287	0.043^a	0.332	0.029^a	-0.244	0.038^a
AGA-IgA	-0.325	0.009^a	-0.266	0.035^a	0.384	0.024^a	0.324	0.010^a	0.325	0.009^a	-0.266	0.035^a
AGA-IgG	-0.332	0.008^a	-0.271	0.022^a	0.298	0.010^a	0.297	0.011^a	0.253	0.031^a	-0.279	0.017^a
Anti-t TGA	-0.342	0.007^a	-0.28	0.017^a	0.305	0.009^a	0.311	0.004^a	0.280	0.035^a	-0.294	0.028^a
Anti-t TGG	-0.35	0.00^a	-0.316	0.004^a	0.315	0.007^a	0.34	0.001^a	0.302	0.014^a	-0.304	0.019^a
AGA-IgA¹	-0.313	0.006^a	-0.301	0.026^a	0.334	0.004^a	0.353	< 0.001^a	0.315	0.011^a	-0.319	0.013^a
AGA-IgG¹	-0.335	0.004^a	-0.324	0.005^a	0.309	0.018^a	0.366	0.023^a	0.349	0.033^a	-0.288	0.045^a
Anti-t TGA¹	-0.261	0.043^a	-0.243	0.035^a	0.376	0.036^a	0.322	0.011^a	0.335	0.009^a	-0.273	0.038^a
Anti-t TGG¹	-0.333	0.032^a	-0.282	0.037^a	0.294	0.031^a	0.305	0.026^a	0.336	0.036^a	-0.314	0.013^a

^aP < 0.05.

¹Demographic characteristics and laboratory parameters are adjusted. BMI: Body mass index; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; CRP: C-reactive protein; AGA-IgA: Anti gliadin antibodies IgA; AGA-IgG: Anti gliadin antibodies IgG; Anti-t TGA: Anti-tissue Transglutaminase IgA antibodies; Anti-t TGG: Anti-tissue Transglutaminase IgA antibodies.

Citation: Kaplan M, Ates I, Yuksel M, Ozderin Ozin Y, Alisik M, Erel O, Kayacetin E. Thiol/disulphide homeostasis in celiac disease. World J Gastrointest Pharmacol Ther 2017; 8(2): 120-126
URL: https://www.wjgnet.com/2150-5349/full/v8/i2/120.htm
DOI: https://dx.doi.org/10.4292/wjgpt.v8.i2.120