Thiol/disulphide homeostasis in celiac disease

Table 2 Dietary compliance of native thiol, disulphide and disulphide/native thiol and its distribution regarding antibody positivity

Variables	Native thiol (μmol/L)	P value	Disulphide (μmol/L)	P value	Disulphide/native thiol (μmol/L)	P value
Diet
GCD (n = 22)	310.6 ± 46.8	0.013a	13.8 ± 3.2	0.034a	5.2 ± 1.4	< 0.001a
GFD (n = 51)	327.9 ± 35.6		12.0 ± 3.3		3.5 ± 1.7
AGA-IgA
(-) (n = 33)	310.5 ± 39.5	0.015a	14.1 ± 3.7	0.020a	4.7 ± 1.9	0.005a
(+) (n = 40)	333.8 ± 40.1		12.0 ± 3.8		3.6 ± 1.4
AGA-IgG
(-) (n = 47)	308.5 ± 36.8	0.027a	13.9 ± 3.1	0.001a	4.6 ± 1.7	< 0.001a
(+) (n = 26)	330.5 ± 45.2		11.1 ± 3.9		3.0 ± 1.1
Anti-t TGA
(-) (n = 29)	315.5 ± 38.2	0.001a	13.9 ± 3.9	0.019a	4.5 ± 1.9	0.007a
(+) (n = 44)	346.2 ± 40.5		11.7 ± 3.8		3.4 ± 1.5
Anti-t TGG
(-) (n = 61)	318.1 ± 37.6	0.002a	13.5 ± 3.9	0.009a		0.035a
(+) (n = 12)	345.3 ± 51.5		10.3 ± 3.0

^aP < 0.05. GCD: Gluten-containing diet; GFD: Gluten-free diet; AGA-IgA: Anti gliadin antibodies IgA; AGA-IgG: Anti gliadin antibodies IgG; Anti-t TGA: Anti-tissue Transglutaminase IgA antibodies; Anti-t TGG: Anti-tissue Transglutaminase IgA antibodies.