A20 inhibits lipopolysaccharide-induced inflammation in enterocytes

Figure 7 Interleukin-8 mRNA expression in different cell groups. 1: A20 overexpression group; 3: A20 overexpression-control group; 2: A20 knockdown group; 4: A20 knockdown-control group; A: Expression of IL-8 mRNA in different groups without LPS stimulation; B: Expression of IL-8 mRNA in different groups with LPS stimulation for 2 h; C: Expression of IL-8 mRNA in different groups with LPS stimulation for 4 h; D: Expression of IL-8 mRNA in different groups with LPS for 8 h. There were no significant differences in the IL-8 mRNA among the different groups without LPS stimulation. At some time points, the expression of IL-8 in the A20 overexpression group was lower than the control group and A20 knockdown group, and the expression of IL-8 in A20 knockdown group was higher than both the control group and A20 overexpression group. ^aP < 0.05, ^bP < 0.01. IL: Interleukin; TNF: Tumor necrosis factor; LPS: Lipopolysaccharide.