Local ablative treatments for hepatocellular carcinoma: An updated review

Table 5 Studies comparing radiofrequency ablation and microwave ablation in hepatocellular carcinoma patients

Ref.	Arm (n)	Study design	Region	CP (A/B/C)	Tumor size (cm)	Number nodules	3-yr survival (%)	Local tumor recurrence (%)
Shibata et al[92]	RFA (36)	RCT	Japan	21/15/0	1.6 (0.7-2)	1.08	NA	8.3
	MWA (36)			19/17/0	1.7 (0.8-2)	1.14	NA	17.4
Lu et al[93]	RFA (53)	R	China	49/4/0	2.6 (1-6.1)	1.35	37.6	20.9
	MWA (49)			39/10/0	2.5 (0.9-7.2)	2.00	50.5	11.8
Ohmoto et al[94]	RFA (34)	R	Japan	20/11/3	1.6 (0.7-2)	1.08	49.0	9.0
	MWA (49)			31/14/4	1.7 (0.8-2)	1.14	70.0	19.0
Ding et al[95]	RFA (85)	R	China	49/36/0	2.38 (1-4.8)	1.15	77.6	5.2
	MWA (113)			75/38/0	2.55 (0.8-5)	1.15	82.7	10.9
Zhang et al[96]	RFA (78)	R	China	78/0/0	NA	1.24	64.1	11.8
	MWA (77)			77/0/0	NA	1.36	51.7	10.5
Abdelaziz et al[97]	RFA (45)	R	Egypt	24/21/0	2.95 ± 1.03+	1.00	NA	13.5
	MWA (66)			25/41/0	2.9 ± 0.97	1.00	NA	3.9
Vogl et al[98]	RFA (25)	R	Germany	NA	NA	1.28	72.0	9.4
	MWA (28)			NA	NA	1.28	79.0	8.3

CP: Child-Pugh; RFA: Radiofrequency ablation; MWA: Microwave ablation; RCT: Randomized controlled trial; R: Retrospective.