Efficacy and safety of botulinum toxin in treatment of anismus: A systematic review

Table 1 Assessment of the methodological qualities of the comparative studies included in the review

Items	Farid et al[12], 2009	Farid et al[20], 2009
Inclusion criteria	1	1
Exclusion criteria	1	1
Comparable demographics	1	1
Number of participating centers is stated?	1	1
The number of surgeons is stated	0	0
Reporting where the authors were on the learning curve	0	0
Clearly stated diagnostic criteria for clinical outcomes	1	1
Adequate description of surgical technique	1	1
Standard surgical technique	1	1
Standard perioperative care	0	0
Age and range are given for patients in BTX-A group	1	1
Statement about any missing data	0	0
Age and range are given for patients in the comparative group	1	1
Patients in each group treated along similar timelines	1	1
The patients asking to enter the study, did they actually take part to it?	0	0
Statement about drop-out rates	0	0
Clearly defined outcomes	1	1
Availability of blind assessors	0	0
Assessment tools were standardized	1	1
Was the analysis by intention to treat?	0	0
Score	12	12

Yes = 1, no (not reported) = 0; Total score = 21, < 8 = poor quality; 8-14 = fair quality and > 14 = good quality. BTX-A: Botulinum toxin type A.