Oral tolerance is inducible during active dextran sulfate sodium-induced colitis

Figure 2 Ovalbumin-specific IgE concentrations in the sera of mice with and without dextran sulfate sodium colitis. On day 63, serum OVA-specific immunoglobulin E (IgE) concentrations were measured by ELISA. The mice that were i.g. administered OVA exhibited significantly lower OVA-specific IgE concentrations (closed bar) than the control mice (open bar) both in the presence and absence of DSS colitis. All results represent at least two independent experiments with four to six mice in each group. The data are shown as the median and interquartile range. ^bP < 0.01. OVA: Ovalbumin; DSS: Dextran sulfate sodium; ELISA: Enzyme-linked immuno sorbent assay; i.g.: Intragastrically.