Orally administered extract from Prunella vulgaris attenuates spontaneous colitis in mdr1a-/- mice

Figure 5 Vehicle-treated mdr1a^-/- mice with severe colitic inflammation developed serum antibody to antigens derived from gut microbiota while those treated with prunella vulgaris extract do not. Whole cell sonicates of three separate clostridial species present as part of the intestinal microbiota (altered Schaedler flora members 356, 500 and 502) were subjected to SDS-PAGE. Western blot analysis was performed using sera collected at necropsy. Antigens in lanes represented in each panel are as follows from left to right: ASF502, ASF500 and ASF356.